Brooklyn Nets general manager Sean Marks discovered Kevin Durant’s plans for free agency the way everybody else did: By Instagram.How Marks knew Durant was being sincere? K.D. wasn’t using a burner account. But we digress.As you can imagine, Marks was interested in knowing why Durant was throwing in with his outfit. Appearing on WFAN on Tuesday, Marks quoted Durant as saying, “I love how you guys play. I see how hard you guys play. You were never out of games. We could never …
DNA is packed like spaghetti in a basketball (07/28/2004), but must constantly be accessed by transcribers, duplicators and other molecular machines. Scientists at the Karolinska Institute, according to EurekAlert, have found a complex of protein machines that know how to untangle DNA. Machines that can keep DNA from separating too early (cohesins) and keep DNA coils compact (condensins) have been studied extensively, but these scientists looked more at another mechanism. When they artificially perturbed DNA strands, the machines went to work fixing the damage:The research group has studied the third, less well understood, protein complex, known as the Smc5/6 complex. This protein complex was found to bind to locations on the DNA strand that the researchers had artificially damaged, suggesting that it is directly involved in the repair process. Moreover, the Smc5/6 complex also seems to be required for the disentanglement of undamaged chromosomes before cell division. If these tangles, which are a natural consequence of the DNA copying process, are left unresolved the chromosomes cannot be separated and sent to the two nascent daughter cells. Like in the repair process, the Smc5/6 complex appears to resolve these intertwines by direct interaction with the DNA molecules, but this process is differently regulated as compared to the function in repair.The press release starts with a “wow” factoid: “Every second, the cells constituting our bodies are replaced through cell division. An adult human consists of about 50,000 billion cells, 1% of which die and are replaced by cell division every day.” Machines like the Smc5/6 complex are essential to maintaining our genomic integrity.So, evolutionists, tell us again about how this all worked out in the mythical RNA world when none of these repair and maintenance mechanisms had yet accidentally emerged.(Visited 8 times, 1 visits today)FacebookTwitterPinterestSave分享0
31 August 2004South Africa added two more silvers to its medal tally as the Athens Olympics concluded, to finish with six medals in all, an improvement of one over Sydney in 2004.In the last three days of competition Hestrie Cloete and Mbulaeni Mulaudzi ended second in the high jump and 800 metres respectively. Given the two athletes’ form going into the competition, the first result was a minor disappointment, the second a major triumph.Cloete outclassed on the nightCloete came up against Yelena Slesarenko who, coming into the competition, was tied with her for the highest clearance in the world in 2004 of 2.04 metres.Paralympic Team SA rocks! – It was a case of saving the best for last as Zanele Situ, who successfully defended the javelin title she won in Sydney four years ago, was awarded the Whang Youn Dai Overcome prize at the close of the Athens 2004 Paralympic Games.The South African, though, entered the event with all the qualifications to make her the gold medal favourite. She was the IAAF’s female athlete of the year in 2003. She was also unbeaten in Golden League competitions in 2004.Both jumpers started out beautifully, clearing on their first six attempts, from 1.89 metres all the way through to 2.02 metres. Cloete then experienced her first failure at 2.04 metres. Slesarenko immediately put the pressure on with a comfortable clearance.Cloete lined up her next jump with determination etched on your face. She charged hard at the bar, but got her run-up wrong and had to duck under the bar, costing her a jump and leaving her with only one more attempt.The two-time world champion decided to move the bar up by two centimetres for her final jump to 2.06 metres, equal to her lifetime best. It was a brave decision, but it didn’t come off as Cloete again failed to clear.Ironically, when Slesarenko went over first time at 2.06 metres she did what Cloete had done when she won the World Championships in 2003 – first-time clearances all the way to 2.06 metres.Mulaudzi puts troubles behind himMbulaeni Mulaudzi’s silver in the 800 metres came as something of a surprise, despite the fact that for most of 2004 he was ranked number one in the world. He had struggled with illness and injury in the lead-up to the Athens Games, and as a result his form was not what it might have been.Nonetheless, he booked his place in the final with two decent runs in the heats and semi-finals. Hezekiel Sepeng, the silver medal winner in the fastest Olympic 800 metres final in history in Atlanta in 1996, also went through as the second of the fastest losers.In the final Mulaudzi put all his trials and tribulations behind him to move up one position from the third place he had achieved at the World Championships in Paris last year to capture silver.Russia’s Yuri Borzakovskiy snatched gold in 1:44.45, while Mulaudzi out-kicked world record holder Wilson Kipketer to finish second in 1:44.61 to the 1:44.65 of the great Dane. Sepeng finished sixth. Update 5 – So close for Van CollerUpdate 4 – SA’s first rowing Olympic medalUpdate 3 – Archer, beach volleyballers shineUpdate 2 – Schoeman bags another medalUpdate 1 – SA swimmers stun the world Relay disasterOther South African competitors were less successful. The men’s 4x400m relay failed to finish in the heats for the final after a botched baton change.Arnaud Malherbe, a member of the quartet, reckoned fellow team member Hendrick Mokganyetsi said the baton was knocked out of his hand by a Russian athlete at the first handover. Mokganyetsi ran back to pick the baton up, but then decided not to continue as the rest of the teams had already roared on by.Bright future for Sandler16-year old Stephanie Sandler failed to qualify for the all-round competition of the rhythmic gymnastics competition. However, her showing of twenty-second overall was more than decent, especially considering her young age. Sandler still has plenty of time to improve, develop, and learn, and better things can be expected of her in the future.Hockey: three greats retireSouth Africa’s women’s hockey team ended their tournament on a high, edging out Spain 4-3 in extra time to finish in ninth place. The final placing was a disappointment because the side failed to play to its potential in some games. That was emphasised when Germany won gold against the Netherlands; earlier in the competition South Africa had outclassed the Germans 3-0.The South African men’s team finished tenth after another tough loss, as had been the case throughout much of the tournament. Facing Great Britain, Craig Jackson and company went one goal down in the forty-third minute, but just two minutes later Greg Nicol leveled the scores at one-all.Neither team was able to break the impasse. With that, the match ultimately moved into penalty strokes and Great Britain emerged 4-3 winners from the spot.The match also brought to an end the careers of three of South Africa’s greatest hockey players ever. Gregg Clark retired as the country’s most capped player of all time, having reached the 250-Test mark in Athens.Captain, Craig Jackson, who reached 200 caps at the Olympics, also called it a day, while Greg Nicol, too, decided to call it quits after an extraordinary career. In 200 matches he scored almost 250 goals, a record good enough to qualify him as one of the all-time greats.Fighters: another dayDuncan Mahlangu failed to move beyond the preliminary round of the 68-kilogram category in the Taekwondo competition, going down to Gabriel Sagustume of Guatemala. He could have had another opportunity to move on had Sagastume won his next bout, but when he lost Mahlangu’s Olympic competition was over.Wrestler Shaun Williams was eliminated when he suffered defeats to the other two men in his 55-kilogram elimination pool. Bulgaria’s Velikov Radoslav easily beat the South African 13-2, but it was tight against China’s Zhengyu Li, who claimed a 5-4 victory. Interestingly, Li went on to defeat Radoslav.Finally, the marathonThe final event of the Olympics, as is traditional, was the marathon, run over a hilly course. Early on South Africa’s trio of Hendrick Ramaala, Ian Syster, and Gert Thys looked strong, running up at the front of the race and setting the pace.However, that strong running signaled only a false dawn as both Syster and Ramaala fell out, with Thys going on to finish in sixteenth place.SA’s Olympic medal winnersGoldMen’s 4x100m freestyle relay team (Roland Schoeman, Lyndon Ferns, Darian Townsend, Ryk Neethling) in a world record 3:13.17SilverHestrie Cloete – women’s high jump, 2.02 metresMbulaeni Mulaudzi – men’s 800 metres, 1:44.61Roland Schoeman – men’s 100 metres freestyle, 48.23BronzeDonovan Cech / Ramon Di Clemente – men’s rowing pairs, 6:33.40Roland Schoeman – men’s 50m freestyle, 22.02 Want to use this article in your publication or on your website?See: Using SAinfo material
“She has worked fantastically during the time since we met. When we started in November she lost to the number 42 in Canada and a month ago she beat the Canadian number one,” said Hogstedt. He also defeated other number one ranked players like Pat Rafter, Jim Courier, Yevgeny Kafelnikov and Guillermo Vilas. He won the US Open Junior event in 1981 and reached a career-high ranking of number 38 in the world. “Zoe plays an aggressive game from the baseline, but she can play with high spin and angles. She also likes to come to the net and serves well, so she has a great all-around game and has a liking for all surfaces,” he said. Looking ahead, he said: “I took Wozniacki, Li Na and Sharapova to the top. Next it will be two young sisters from South Africa, Zoe and Isabella Kruger, who I will make Grand Slam champions for South Africa.” He then discovered that Kruger, who comes from Pretoria, had an equally talented younger sister, Isabella, who is just eight years old. “I saw from the first day I could transform Zoe Kruger into one of the best players in the world,” Hogstedt said in a statement on Wednesday. Thomas Hogstedt, one of the world’s leading tennis coaches, has identified two South African sisters as potential future Grand Slam champions and has taken them under his wing. “Isabella reminds me of Martina Hingis. She plays a very fast, flat game and has great feel for the ball. Her favourite shot is the volley, but she also hits a very good drop shot.” Hogstedt comes to South Africa whenever he is able to, but has a coaching team who work with the girls when he can’t travel. The girls also go to his facility in Sweden for training camps and he and his coaching team travel with the girls when they play on the international circuit. His almost three-year coaching relationship with Maria Sharapova came to an end in July this year. The Swede, who has guided the likes of Maria Sharapova, Li Na and Caroline Wozniacki to the pinnacle of their careers, was invited by Tennis South Africa to conduct a clinic in Stellenbosch last November. At the clinic, he came across then 10-year-old Zoe Kruger, who immediately caught his eye. Zoe also helped South Africa to a third place finish in the under-12 team championship in Canada. Hogstedt knows what it takes to play at highest level of the game. In his 14-year professional career he managed wins over all three Swedish players who were ranked number one in the world at some stage during their careers: Bjorn Borg, Mats Wilander and Stefan Edberg. Uncanny abilityHogstedt has an uncanny ability to recognise what it takes to turn a pre-teenager into a champion, as he proved when coaching Wozniacki as a 13-year-old. He took her to number one in the world. SAinfo reporter One of the bestIsabella is already regarded as one of the best eight-year-old players in the world. She reached the final of the highly regarded Little Mo tournament in the under-eight age group when she was just seven and lost the final in three sets to Russia’s number one player. 26 September 2013 Coaching careerAs a coach he has worked with some of the top names in the sport, including Germany’s Tommy Haas and Nicolas Kiefer. Hogstedt also coached three top Swedes Jonas Bjorkman (career high world number 4), Magnus Norman (ranked 2) and Thomas Johansson (ranked 9). No peersZoe has no peers in her age group in South Africa, which she demonstrated by winning the SA National Under-12 Championship when she was just 10 years old. Last month she reached the final of an under-12 tournament in Canada, winning five of her six matches.
Tags:#start#StartUp 101 sramana mitra Why Tech Companies Need Simpler Terms of Servic… Top Reasons to Go With Managed WordPress Hosting 8 Best WordPress Hosting Solutions on the Market Related Posts A Web Developer’s New Best Friend is the AI Wai… For this week’s One Million by One Million roundtable, we started off by announcing a new deal through which the 1M/1M-Persistent Systems partnership has decided to back Indian company, OrangeScape. So the first company I want to discuss today is OrangeScape, before I move on to today’s presenters. OrangeScape positions itself as an Application Platform As A Service (APaaS) provider, and has some marquee customers in India including Unilever, Citibank, Pfizer, AstraZeneca, and Sterlite. They will now be leveraging the 1M/1M-Persistent channel to go to market in the United States.What caught my attention as I started working with OrangeScape is their proven ability to plug a distinct gap in Google’s enterprise solution. As you know, the Google productivity apps portfolio is getting very good traction within enterprises, and through our Thought Leaders in Cloud Computing series, we’ve heard from various CIOs who are moving from Lotus Notes or Microsoft Exchange to Google’s Office suite. One of the primary drivers of the switch is cost. A second is collaboration.Currently, when enterprises switch to Google’s productivity suite, they still need to make provisions to move the large portfolio of home grown long tail productivity apps that have been developed around the previous system – Lotus Notes or Microsoft Exchange. And in comes the Google App Engine as Google’s offering in this context.Well, it turns out that to port long tail productivity apps to Google’s App Engine is a somewhat cumbersome job, and requires a lot of custom development. Building new apps is also not as simple.Enter OrangeScape.The long tail apps can easily be ported to or developed on Google App Engine in a third of the time and cost using OrangeScape as an application platform. Voila, the entire productivity suite of an enterprise can become cloud-ready, quickly, efficiently, and cost-effectively!I have long been a champion of Indian product companies, urging the entrepreneurs to think beyond labor arbitrage and outsourcing. Today, I am thrilled to see that OrangeScape is emerging as a promising player in the Indian startup firmament, and reaching for global market penetration.Multi Angular Force GeneratorNext, Paul Croskrey with OBM Global pitched the Multi Angular Force Generator (MAFG), an alternative energy startup aiming to provide off-grid power. The MAFG claims to create huge amounts of horsepower and torque, enough to drive the largest generators made today. The MAFG Thermal Reactors utilize thermal storage tanks heated to high temperatures to produce steam allowing it to run a variety to operations ranging from waste purification to running steam turbines making electricity.Paul says that he wants commercial operations to use this off-grid power supply, and help companies like Wal-Mart save costs. Wal-Mart, in fact, is interested in testing the module at one of their warehouses.Paul’s bottleneck, however, is validation. He needs some knowledgeable and credible people to validate that the technology for which OBM already has issued patents, works, or at least has the potential to work. No investment is possible without that validation, whether it is government grants (and there is quite a bit of that available for clean energy projects) or angel or venture capital. It is not possible for financial investors to gauge the viability of this technology without some help from scientists and researchers.I advised Paul to find a scientist with enough credibility in this field, and invite him/her as a cofounder / Chief Scientist. This is an essential step that will be necessary for Paul to take. It is squarely in his critical path, blocking all sorts of financing options, and unfortunately, he cannot really make progress with this venture without some external financing. It’s simply a capital-intensive business that needs money.MomaresFinally, Marcos Menendez presented Momares, a nifty piece of technology to help small businesses market themselves through coupons delivered through opt-in SMS subscriptions. For his go-to-market strategy, Marcos has identified the bowling center market. He says that bowling centers are a booming sector, but they have a very specific problem: they lack traffic during weekdays. Well, Marcos, using his technology, believes he can increase weekday utilization by 200% – a very bold and robust ROI value proposition. I asked him to create a couple of success stories to validate the assumptions, and then do a very focused PR campaign in the blowing center industry.Of course, the solution applies to a much broader set of small business customers, making this an attractive business opportunity. I recently did a story on 3CInteractive that has built a $40M business based on a similar value proposition, but catering to large enterprises.Someone from the audience asked how Momares differs from Groupon. Well, to get the discount on Groupon, consumers have to do some work – recruit other consumers – whereas Momares offers a straightforward opt-in coupon to your favorite business, whether it is a spa, a restaurant, or a bowling center.Bottom line, I like this business!You can listen to the recording of today’s roundtable here. Recordings of previous roundtables are all available here. You can register for the next roundtable here.Sramana Mitra is the founder of the One Million by One Million (1M/1M) initiative, an educational, business development and incubation program that aims to help one million entrepreneurs globally to reach $1 million in revenue and beyond. She is a Silicon Valley entrepreneur and strategy consultant, writes the blog Sramana Mitra On Strategy, is author of the Entrepreneur Journeys book series and Vision India 2020. She has a master’s degree in electrical engineering and computer science from the Massachusetts Institute of Technology.Photo by ilco