first_img © 2013 Phys.org This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: via Nanotechweb Gold-plated nano-bits find, destroy cancer cells Explore further (Phys.org) —A combined team of researchers from Portugal and Spain has found that it might be possible to use nanographene oxide to help improve the tumor killing capability of chemo, radiotherapy or laser treatments in cancer patients. In their paper to be published in the journal Nanotechnology, the team describes tests they’ve conducted with nanographene materials and how they might be used in medical applications. Citation: Researchers looking to use nanographene oxide to destroy tumors (2013, November 26) retrieved 18 August 2019 from https://phys.org/news/2013-11-nanographene-oxide-tumors.html Journal information: Nanotechnology Scientists have learned over the years that the cells in cancerous tumors are more sensitive to heat than normal cells in the body (it makes them more porous). To take advantage of this property, researchers have developed techniques for heating such cells before applying other techniques meant to kill them—heating tumors before using chemo or radiotherapy makes them more vulnerable (the drugs can more easily enter the tumor cells due to the enlarged pores) and thus easier to kill. In this new effort, the research team has been experimenting with nanographene oxides, which they say, might conceivably be used as a means for more accurately directing heat to tumor cells prior to using other tumor killing techniques.In their lab, the researchers have been firing lasers at live cells and irradiating them to test for culture temperatures variances under different conditions. To improve the results, they’ve been soaking the cells in graphene oxide first—the cells absorb the foreign material. In analyzing the results, the researchers have found that doing so causes cell necrosis (death) and a subsequent increase in the release of cytokine (substances secreted by immune system cells) to the surrounding environment. They also noted that the increased temperature of the cells treated with the nanographene oxide performed better when increasing the power of the laser than when increasing exposure time, which is preferential because it means less damage is caused to surrounding healthy tissue. They also suggest that if their technique were to be used in live patients, it might be possible to customize the type of cell death that results—in effect tailoring the response of immune cells.Unfortunately, it’s still not known if soaking a real tumor in nanographene oxide before applying other measures might have other undesirable side effects. Thus, a lot of testing will have to be conducted before they can be tried in human patients. But if the preliminary results pan out, nanographene oxide and/or other similar materials might one day be used to help conventional treatments work better.last_img read more

first_imgRecently, the other old hand in this new biochemistry, Craig Venter, asked Church during an interview if everything would still be copacetic—in other words, if mirror drugs and enzymes would really perform the exact same way in the mirror world. While drug companies may be salivating after Church’s short-latency positive answer, there is some intriguing evidence that more subtle symmetry-breaking electron spin effects could be at play. In one such conception, electrons originally in heterogenous spin states are released from an enzyme (like NADH synthase) and are subsequently filtered and polarized as they pass through chiral α-helix structures to the site of amino acid synthesis at the other end. This effectively produces “spin up” electrons that, if you can excuse the jargon, participate in the reductive reaction between α-oxo acid and ammonia with only L-amino acids forming according to the Pauli exclusion principle. In any event, to look in the mirror on the wall and see a biology that does not behave exactly like ours would seem to require some significant new parity breakdown in physics, to say the least.Now, olfaction is probably the space where these deuterium switches and chiral switches most informatively converge to elucidate how receptors might operate. In fact, the authors explicitly highlight the fact that their histamine receptor model may have something to say about olfactory receptors. Importantly, both of these receptor classes belong to the so-called GPCR (G-protein coupled receptor) family that vertebrates use to detect odorants; half of our own 800 GPCRs are provisioned almost exclusively to olfaction.The author’s main comments, here, center on the aromatic groups of molecules, features that are typically associated with delocalized electrons. For example, the imidazole ring of histidine (histamine’s the amino acid precursor) is aromatic at all pH values; four of its pi electrons form two double bonds and two from a nitrogen lone pair. The authors propose that a major fallout of deuteration is that the aromatic moiety shrinks the effective C–D distance relative to its C–H value. Aromatic C–H bonds act as proton donors and form weak hydrogen bonds with water molecules and proton acceptors at the receptor binding site. In other words, that deuterated odorants would be a little different from nondeuterated odorants—something that has actually been appreciated for some time. These comments are pointed straight at recent experiments by Luca Turin, who has advanced the theory of molecular vibration sensing in olfaction in which the nose performs an analysis akin to your favorite benchtop device. Depending on the interpretation, that instrument might be part mass spectrometer, part IR spectrometer, and part scanning tunneling microscope. In particular, they question the conclusion of Luca’s group that flies conditioned with progressively deuterated acetophenone could readily distinguished between the deuterated and nondeuterated varieties.In response, Luca quickly noted a few problems. For one, he fairly observes, ‘then how come the flies transfer learning from one deuterated compound to another, and from C-D stretch to C≡N ? By their lights, there should only be a difference in affinity. Why is there a commonality in smell character?’Perhaps more pointedly, he notes that there are no aromatic CH groups in his deturerated musk experiments, only aliphatic groups—something the authors wisely avoid citing. Furthermore, the authors don’t mention other work that shows very good correlations between vibrational spectra and agonist activity in histamine receptors.In a recent popular article, Luca has made a beginning toward a theory that puts the odor character back into the molecule. While not necessarily drugs, odors can be considered a special class of molecules with a much restricted receptor requirement. Due to inherent limitations in detecting volatiles, olfactory receptors can only expect to see molecules reflecting some trade-off in general stickiness and solubility—a compromise that makes specificity the frequent casualty. Luca proposed that GPCRs and their activators may be thought of as more like electronic components than the mechanical devices of the shape-based receptor paradigm. He suggests that cells could offer them in three styles—vibration (V), tunneling (T), and redox (R):Type V receptors tunnel electrons across a gap that corresponds to an energy jump by binding a molecule that possesses one or more vibrations at the correct energy. Type T have the same circuit topology, but without an energy jump. The receptor is turned on when a molecule binds to it and includes a feature, such as a positive charge, that lowers the barrier to electron tunneling. Finally, type r receptors only have the output half of the circuit where the ligand brings in the electron, and then undergoes an oxidation step when bound. Notably, GPCRs are frequently considered to be a predominantly Eukaryotic innovation. There is certainly evidence for GPCR precursors among the domains and motifs of proteins in lower life forms. However, bacteria generally go for more direct-acting receptors with efficient built-in ion channels as opposed to the laggy and protracted toggling of separate downstream ion channels actuated by messy G-protein cascades. For example, both bacteriorhodopsin and our rhodopsin belong to the ‘seven transmembrane domain’ family of proteins, but while rhodopsin is a GPCR, the ancient light-powered bacterial ion pump is probably not.Why is this the case? If the primary job of sensory neurons is simply to encode incoming information into spikes, then what could be better than speedy ligand gated ion channels? One hint is the observation that if mitochondria generated or otherwise quickly fell out of the advent of eukaryotism, and GPCRs were an integral part of that transition, then the expected intracellular effect from GPCRs might be direct control of the locally resident mitochondria. As possible counterpoint, here, one might point to those rare birds, the infinitesimal fairy flies that inexplicably jettison away much of their own neuronal nuclei and mitochondria and basically run on fumes till they expire. Such creatures might still sense and smell, but how well do they really do it? Explore further Citation: Using the ‘deuterium switch’ to understand how receptors work (2016, June 7) retrieved 18 August 2019 from https://phys.org/news/2016-06-deuterium-receptors.html The authors measured changes in the binding affinities of histamine receptor ligands after they replaced the normal buffer solution with D20 (deuterium oxide). In contrast to other kinds of studies in which the ligands themselves had deuterium permanently bound to carbon atoms, a heavy water solution would deuterate the ligand at exchangeable N-H and O-H protons. This trick directly targets the hydrogen bonds that presumably control ligand-receptor interactions and associated ligand-water interactions.There is no shortage of ways in which an extra neutron perturbs the life of a molecule. A two-fold mass gain decreases bond length and increases bond strength. This ultimately changes a number of physical and chemical properties, including molar volume, polarity, electron donation, Van der Waal’s forces, dipolar moment, and lipophilicity. For example, deuterated caffeine is known to elute faster in the lab on a gas chromatograph mass spectrometer. One might even imagine trying to capture nature’s most elusive superbuzz by drinking it. Depending on which of caffeine’s methyl groups were originally deuterated, the cytochrome 450 enzymes that kick off its transformation in your liver (ultimately to formaldehyde) would likely balk at the enzymatically more resistant C-D bonds. This will delay the formation of some metabolites, creating a relative preponderance of others.To put this so-called ‘deuterium switch’ into the perspective of a larger business model, consider another devilish operation known in the pharmaceutical world as a ‘chiral switch.’ While often performed in much the same spirit as the deuterium shuffle, the creation of mirrorland molecules is arguably an even more significant, qualitative, and less predictable transformation. A recent radical report documents the creation of a ‘reverse’ DNA polymerase, presumably constructed from mirror image ‘D’ (or right-handed) amino acids. This polymerase has the ability to write mirror image DNA that winds to the left (as opposed to threading like a familiar right-handed screw).The beauty of this emerging “looking-glass” world is that the southpaw polymerase has some unexpected talents—for one, it also writes RNA. Furthermore, researchers like George Church are already on their way to building mirror ribosomes that could be fed this mirror-RNA. Therapeutic mirror RNAs and proteins would have an unparalleled diplomatic immunity in the cell, rendering drugs made from them virtually untouchable by straight enzymes, in many respects upgrading the old Windows 32 cellular OS to 64-bits. Recept concepts. Credit: Luca Turin Plausibility of the vibrational theory of smell More information: Mojca Kržan et al. The Quantum Nature of Drug-Receptor Interactions: Deuteration Changes Binding Affinities for Histamine Receptor Ligands, PLOS ONE (2016). DOI: 10.1371/journal.pone.0154002 (Phys.org)—The market value for deuterated drugs has recently been estimated at over a billion dollars. Such drugs are simply molecules in which one or more hydrogen atoms are replaced with deuterium. While these kinds of manipulations are known to work wonders as far as breathing new life into aging patents, the overall therapeutic value of this medical manna can be contentious. A recent paper published in PLoS ONE seeks to explain the ‘quantum nature of drug-receptor interactions’ under deuteration using a combined experimental and computational approach. Although a tall order, a more comprehensive and predictive theory of receptor interactions is sorely needed. Perhaps a theory in which the molecular character of drug effects are written less into the receptor and more into the drug itself. © 2016 Phys.org Journal information: PLoS ONE This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

first_imgA team of researchers affiliated with institutions in Argentina, the U.S. and Germany has found that there is a way to improve on the “wisdom of the crowd”—separate the people in a given crowd into smaller groups and let them talk about an issue at hand before an answer is given. In their paper published in the journal Nature Human Behavior, the group describes an experiment they carried out with a large crowd of volunteers, and what they learned from it. Most people have heard of the “wisdom of the crowd,” in which individuals in a crowd are privately asked to give an answer to a question, such as how many jelly beans are in a jar. When averaged together, the answer given by the crowd will generally be better than for any given individual. Now, it appears there may be a way to improve the accuracy of a crowd.Some sociologists have suggested that allowing participants in a crowd to talk to one another before giving “wisdom of the crowd” answers would reduce the accuracy of the final average answer because it would likely lead to a herd mentality. The results of the experiment in this new effort suggest such thinking is wrong.In their experiment, the researchers asked 5180 people at a 2015 TED talk in Buenos Aires to answer several simple questions, such estimating the height of the Eiffel Tower, or the number of goals scored in the 201 FIFA World Cup. Each of the respondents was asked to give an answer privately, and then to join with a group of four other individuals to discuss the question. After one minute on each topic, each of the groups was asked for mutually agreed-upon answers to the same questions.The researchers report that the average answers of the 280 groups of five (not all of those who answered the question individually were willing to join a group) was 49.2 percent more accurate than the average crowd response as a whole. This, the team suggests, indicates that allowing some logical discussion into the equation can improve results. © 2018 Phys.org Journal information: Nature Human Behaviour Is that your final answer? Study suggests method for improving individual decisions Explore furthercenter_img More information: Joaquin Navajas et al. Aggregated knowledge from a small number of debates outperforms the wisdom of large crowds, Nature Human Behaviour (2018). DOI: 10.1038/s41562-017-0273-4AbstractThe aggregation of many independent estimates can outperform the most accurate individual judgement1,2,3. This centenarian finding1,2, popularly known as the ‘wisdom of crowds’3, has been applied to problems ranging from the diagnosis of cancer4 to financial forecasting5. It is widely believed that social influence undermines collective wisdom by reducing the diversity of opinions within the crowd. Here, we show that if a large crowd is structured in small independent groups, deliberation and social influence within groups improve the crowd’s collective accuracy. We asked a live crowd (N = 5,180) to respond to general-knowledge questions (for example, “What is the height of the Eiffel Tower?”). Participants first answered individually, then deliberated and made consensus decisions in groups of five, and finally provided revised individual estimates. We found that averaging consensus decisions was substantially more accurate than aggregating the initial independent opinions. Remarkably, combining as few as four consensus choices outperformed the wisdom of thousands of individuals. Credit: CC0 Public Domain Citation: Crowds within crowd found to outperform ‘wisdom of the crowd’ (2018, January 18) retrieved 18 August 2019 from https://phys.org/news/2018-01-crowds-crowd-outperform-wisdom.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

first_imgA team of researchers from Japan, the U.S. and China, has identified a topological superconducting phase for possible use in an iron-based material in quantum computers. In their paper published in the journal Science, the team outlines their study of the phase, which, they claim, shows promise as a means for solving the decoherence problem in quantum computers. Citation: Topological superconductor phase may solve decoherence problem in quantum computers (2018, March 9) retrieved 18 August 2019 from https://phys.org/news/2018-03-topological-superconductor-phase-decoherence-problem.html Journal information: Science This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. As research surrounding quantum computers continues researchers confront a number of problems. One is the tendency of quantum states to degrade, resulting in computing errors—a problem known as decoherence. Experts suggest that the solution to the problem is to develop a material capable of protecting the quantum state by employing just the right topological properties. In this way, localized noise would not be able to disturb the quantum state. In this new effort, the researchers report on the identification of a topological superconducting phase that they believe could satisfy this requirement.The researchers report that they were able to attain three key kinds of measurements believed to be necessary for analyzing the quantum phase of Fe(Te, Se) in sufficient detail, which they claim shows that the phase could prove suitable for protecting the quantum state in a system. They further report that the phase, once integrated into a suitable material, would be capable of supporting Majorana bound states (MBSs), which are quasiparticles so-named due to their discovery by Ettore Majorana. Prior research has suggested that a material capable of using Majorana properties might play a role in solving the decoherence problem. The researchers note also that they were able to identify the helical spin polarization of the surface state and to measure the superconducting gap. They were also able to identify the surface state. Taken together, the results of their testing indicate that MBSs could be induced in a material by exerting a magnetic field to the Fe(Te, Se). If their predictions pan out, the new phase could wind up as part of the next generation of quantum computers, possibly paving the way for machines capable of manipulating more qubits than those currently in use. © 2018 Phys.orgcenter_img More information: Peng Zhang et al. Observation of topological superconductivity on the surface of an iron-based superconductor, Science (2018). DOI: 10.1126/science.aan4596 , science.sciencemag.org/content … 3/07/science.aan4596AbstractTopological superconductors are predicted to host exotic Majorana states that obey non-Abelian statistics and can be used to implement a topological quantum computer. Most of the proposed topological superconductors are realized in difficult-to-fabricate heterostructures at very low temperatures. Here by using high-resolution spin-resolved and angle-resolved photoelectron spectroscopy, we find that the iron-based superconductor FeTe1-xSex (x = 0.45, superconducting transition temperature Tc = 14.5 K) hosts Dirac-cone type spin-helical surface states at Fermi level; the surface states exhibit an s-wave superconducting gap below Tc. Our study shows that the surface states of FeTe0.55Se0.45 are 2D topologically superconducting, providing a simple and possibly high temperature platform for realizing Majorana states. Credit: CC0 Public Domain Unconventional superconductor may be used to create quantum computers of the future Explore furtherlast_img read more

first_imgCourt Limits Display Of South Africa’s Old Apartheid… Denis Farrell by NPR News Bill Chappell 8.21.19 11:30am A South African court is restricting gratuitous displays of the country’s old apartheid-era flag, calling the banner “a vivid symbol of white supremacy and black disenfranchisement and suppression.” The flag was the official standard of South Africa from 1928 until the end of apartheid in 1994, when it was replaced by a six-color flag whose Y-shape symbolizes unity. On Wednesday, the Equality Court ruled that the old flag is “a symbol that immortalizes the period of a system of racial segregation, racial oppression through apartheid, and of South Africa as an international pariah state that dehumanized the black population.” The lawsuit was filed by the Nelson Mandela Foundation, which said displaying the apartheid flag amounted to hate speech, unfair discrimination and harassment against black people. “Judge Phineas Mojapelo of South Africa’s Equality Court delivered the ruling to restrict the use of the orange, white and blue flag of the former white minority regime,” NPR’s Ofeibea Quist-Arcton reports. “However, he said the move was not a complete ban, because use of the divisive flag associated with the apartheid years is protected by law for artistic, academic, journalistic and other purposes in the public interest.”The suit targeted a group called AfriForum, which is widely seen as representing the views of a conservative white minority of Afrikaners. In court, AfriForum’s representatives contended that South Africa’s hate speech laws apply only to words, not symbols. They also said that under the constitution, displaying the flag is a protected expression.”Simply displaying it, in our view, is not sufficient for it to be hate speech,” AfriForum Head of Policy and Action Ernst Roets said after the court released its decision. “For it to be hate speech, it has to be coupled with some form of a call to action to inflict harm or something to that effect.”On Wednesday, the Nelson Mandela Foundation said the 1928 flag has become a global symbol of white supremacy and hatred “and is considered by most South Africans as a source of trauma and terror.”The foundation filed suit after the flag appeared at protests in late 2017 that decried deadly attacks on white farmers. Those protests, dubbed “Black Monday,” were promoted by AfriForum.In siding with the Mandela foundation, the Equality Court ruled that in addition to being racist, gratuitous display of the old flag “demonstrates a clear intention to be hurtful” and to promote hatred against black people.Given the flag’s adoption by a whites-only parliament and its six decades of symbolizing the apartheid era, the court said, “It is thus, not surprisingly, viewed differently even today by mostly white people on the one hand and black people on the other.”Copyright 2019 NPR. To see more, visit NPR.last_img read more

Are you a dog lover? Then here is an evening dedicated to man’s best friend that you must visit.‘A cause 4 The Paws’ is an effort to find loving homes for abandoned pets and other Indian street dogs. The event is in collaboration with Delhi Police Dog Squad and PFA to commemorate World Animal Day. It aims to find homes for abandoned dogs who were pets abandoned by their families. They have found their way to the animal shelters, but are now looking for new loving homes. Also Read – ‘Playing Jojo was emotionally exhausting’The event would feature shows which include  Delhi Police Dog Show: A display of obedience, sniffing and tracking by the canine sentinels. The performance will showcase extraordinary talents and immaculatetraining. The squad will consist of about 50 dogs who will display some spectacular drills.Next would be ‘Carnival Of Animals’, a dance performance by Nikolina Nikoleski preaching the importance of animals to mankind. From the smooth moves of a wild cat, the gallop of zebra and horse, to the flight of butterflies, the dancers will create the aura of the jungle. The choreography celebrates the spirit and affection of animals toward humans.The highlight of the event will be a catwalk by abandoned dogs. Pedigrees, mixed breeds/Indian breeds and special dogs would together walk the runway.Be there.DETAILWhen: 13 and 14 OctoberWhere: Amphitheatre, Select Citywalk, Saket Timings: 5 pm onwards read more

first_imgKolkata: The anti-burglary section of Kolkata Police’s Detective Department solved three major burglarycases within a span of one month. The sleuths not only nabbed the criminals but also recovered around Rs 50 lakh of stolen money.According to a source in the detective department, the first case was registered in the last week of May at Posta police station against a person named Babulal Parekh, who had committed criminal breach of trust and duped his employer. He had fled away Also Read – Heavy rain hits traffic, flightswith Rs 34 lakh.Babulal, who was a resident of Rajasthan, had kept his cell phone switched off, which made it difficult for the sleuths to track his movement. The police used modern technology, tracked his bank accounts and finally managed to arrest him from Indore.A major chunk of the stolen money was also recovered.The second case was registered under Shakespeare Sarani Police station by one Sandeep Agarwal, a resident of Middleton Road.Around Rs 16 lakh was stolen from his house. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedThe prime suspect was carpenter Murshed Ali, who was working at Agarwal’s residence.Police raided his probable hideouts in Panskura and Barasat but on both the occasions he managed to elude them.The sleuths questioned his friends and relatives and learnt that Murshed was an alcoholic and regularly visited bars. Police identified a handful of bars in the city and laid a trap and ultimately nabbed him. They also recovered much of the stolen cash.The third case was the cracking of a theft case of Rs 9 lakh from an office under Jorasanko Police Station area. Soon, after investigations revealed the involvement of an insider in the job,police started interrogating the employees and matched their call records with their statement.One of the employees, Biswajit Pathak, after prolonged interrogation, finally broke down and confessed his crime. The amount was recovered from him.It may be mentioned that in all these cases the anti burglary team was led by the officer in charge of the squadChitradeep Pande.last_img read more

first_imgDirector Kunal Kohli’s acting debut Phir Se is yet to get its release date as the filmmaker is not getting a suitable week for it. The Hum Tum director, who is making his foray into acting opposite TV star Jennifer Winget, said he is looking for a good date. “#PhirSe release date being worked. Next few months packed, looking for a good date, once locked music will follow accordingly,” Kunal posted on Twitter.Phir Se, co-directed by Kunal and debut filmmaker Ajay Bhuyan, is said to be based on a separated couple living in London and they are trying to come to terms with the consequences of their split. The trailer of the film released on April 7, 2015. Phir Se was earlier scheduled to hit theatres in May. The film faced legal trouble when writer Jyoti Kapoor filed a suit against the director for copyright infringement.last_img read more

first_imgBALURGHAT: In a significant move, law enforcers and district administration jointly have imposed restrictions on vehicles in Balurghat town for hassle-free traffic movement duringDurga Puja.It has been decided that no vehicle including motorbikes will be allowed in the town for 12 hours between 4 pm and 4 am starting from October 15 to 19.A high-level meeting was conducted at the conference hall of the district administrative building on Tuesday evening. Also Read – Rain batters Kolkata, cripples normal lifeThe meeting was presided over by district magistrate Deepap Priya P.District police chief Prasun Banerjee, additional district magistrate (general) Krittibas Nayak, additional police chief Debasis Nandi, sub-divisional magistrate Isha Mukherjee, district information and cultural officer Shantanu Chakraborty, Balurghat municipality chairman Rajen Shill and Gangarampur municipality chairman Prasanta Mitra were also present.”It is our target to ensure glitch-free Durga Puja. There will be complete restrictions on vehicles and motorbikes between October 15 and 19 from 4 pm to 4 am. TOTO, however, will run in the town to carry passengers as per rules and regulations provided by the local civic body. Besides, a fare-chart will be provided by the municipality shortly to the TOTO pullers to remove any confusion,” the DM said. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killedA joint control-room will be operated by both police and civic body officials.Each puja organiser will get five free entry passes for free movement during restrictions. However, none of them will be allowed to enter in and around 100 meter of the puja pandal.The city people will be provided with two mobile numbers along with Whatsapp facility for any complaint.Notably, the same restrictions had also been imposed on vehicles last year.last_img read more

first_imgKolkata: Kolkata Police has made elaborate arrangements in Park Street which would be enforced from 11:55 pm on Monday to ensure hassle-free Christmas celebration.Enthusiastic city dwellers have started visiting the area since Sunday night and the footfall has been rising since Monday evening. Despite the huge gathering of people, Kolkata Police has managed traffic in such a way that no major congestion occurred in Park Street before its closure for celebration. Sources informed that Park Street and all of its link roads were blocked from 11:55 pm. All Esplanade bound vehicles were diverted through S N Banerjee Road and Exide Crossing. Also Read – Rain batters Kolkata, cripples normal lifePark Street got more and more crowded throughout the day as the festive frenzy took over people. Another attraction which would add to the joy is a musical fountain installed by CESC at Maidan opposite Victoria Memorial. The 150-channel musical fountain has been refurbished and a new programme of music will enthrall the citizens of Kolkata, which has already acquired a special position as one of the most well-illuminated Indian cities. The fountain becomes functional from 5 pm to 9 pm from Christmas Eve. Governor Keshari Nath Tripathi has conveyed his heartiest greetings to the people of Bengal. He wishes that this joyous occasion provides an opportunity to reaffirm our faith in the country’s cultural heritage, spirit of friendship and fraternity among all sections of society. “May the ideals of peace, amity and sacrifice prevail,” the Governor said.last_img read more

first_imgKolkata: The export of jute products and its diversified items has gone up by 24 percent in the last five years, said Union minister for Textile Smriti Zubin Irani.She was addressing a gathering after formally inaugurating the “Artisan Speak and Jute Expo” at the recently restored heritage currency building in the city. It is an outreach initiative of the Union ministry, which will be held here from January 7-10. “We have seen a growth of 24 percent in exports of jute products and diversified products in the last five years. Today we also celebrate the legacy of jute in the country,” Irani said. Also Read – Rain batters Kolkata, cripples normal lifeIt may be mentioned here that delegates from around 14 nations and over 70 buyers are participating in the four-day programme. The Textile industry is the second largest employment sector in India, following the agriculture sector. The sector comprises various fields like cotton, jute, silk, wool, man-made fibres, powerlooms and handicrafts. The event mainly aims at promoting Indian handlooms, handicrafts, silk and jute and providing a platform for marketing and business linkages with both international and domestic buyers. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killedThe organisers believe that it will open new opportunities for artisans to exhibit their products. The theme pavilion has an impressive display of handloom products developed by the weavers, along with live demonstrations of exclusive weaves. One of the main objectives of the programme is to create awareness about the textile industry by inviting international buyers, agents and other marketing organizations, apart from establishing Business to Business (B2B) connects. This also gives a platform for viable marketing to improve exports and domestic presence. Secretary of Ministry of Textiles Raghvendra Singh, who was also present in the programme, said the ministry has been trying to find ways and means to enhance the income of weavers and also to connect them with garment manufacturers to increase their margins. The ministry is also supporting weavers and craftsmen in 40 districts of India, Singh added. The event will also showcase textile expositions by many renowned fashion designers from India and NIFT. The expositions will promote Indian jute, silk, handloom and handicrafts. The visitors can choose from a mix of handloom, handicraft, silk and jute products and learn about GI tagging of Baluchari, the pride of the Bengal heritage in the iconic old currency building.last_img read more

first_imgThe colours, shapes, and emotion have emerged from the very soul of the Capital city, and together they will converge at Open Palm Court gallery, Lodhi Road this autumn.As a part of a group exhibition, titled ‘Panorama-12’ – over 20 artists will bring to the viewers a varying range of interpretation of ranging contemporary issues of social relevance from September 1 till September 6.Curated by Priyanka Banerjee, Panoroma-12, literally meaning an unbroken view of a subject, celebrates the talent of the fresh and the new, and makes a compelling case for contemporary art in the city. Also Read – Add new books to your shelfThe exhibition delves into the contemporary issue of social relevance, such as feminism, ethical treatment of animals, spiritual harmony, global warming and so on. Nature, for instance, is explored through a mutually symbiotic relationship of flora and fauna.Urbanization and industrialization have exploited the natural layers of our ecosystem, and its awareness becomes paramount to awaken our collective consciousness. As each artist touches upon subject such as there that have paralysed the society, their canvas becomes a window for us all to explore the possibilities. This is one of its kind, the event is funded by the artists entirely on their own, therefore there is no question of dependence on sponsors. Also Read – Over 2 hours screen time daily will make your kids impulsiveDabbling in a diverse range of mediums – from watercolour, oil and pen and pencils to mixed media, theartists bring to their canvas emotions that reverberate with social significance.Mridul Chakraborty depicts the joyof festivity through his portrayal of human figures, whereas, Nilay Sarkar reverberates the same mood and shows happiness through vibrant andsoft colours used on his canvas. Then there is, Tapan Das, who harps on his love for nature through his abstract art along with other artists like Meghna, who emphasises on the adverse effects of global warming through her vivacious paintings or the works of Shalini Varshney’s – whose paintings portray spiritual harmony which is lost in our lives. Besides, Biswarajan Bhunia’s paintings resonate the same feelings of Shalini’s. Artists like Rama Sharma and Pooja Gujral have tried to bring colours and happiness into our stressful lives through their vibrant artworks. Another participating artist – Rajeev Semwal has tried to bring before us the songs of nature woven neatly through his traditional artworks.On the other hand, veteran artist Uma Bardhan deals with spirituality while the artworks of the veteran artist Archana Das are an impeccable blend of childlike innocence and adult wisdom.Pankaj Bharti’s paintings are thought-provoking and are beautifully executed with bright colours .Akshita Wason’s paintings done in mixed media portray the changes that are taking place in our environment.last_img read more

first_imgDarjeeling: The Model Code of Conduct eclipsed the celebration of Tagore’s birth anniversary at Mongpu in Darjeeling district this year, as the bard’s 158th birth anniversary was observed on a low key.Though the ministers were not present, the participation of the local community was overwhelming. Even the commemorations had the local flavour that Tagore had adored. Mongpu, situated 33 km from Darjeeling town, was a favourite destination of the bard. He visited the place in 1938 on May 21 and stayed till June. In 1939, he stayed there from May 14 till June 17 to return again on September 12 to stay till the first week of November. Also Read – Rs 13,000 crore investment to provide 2 lakh jobs: MamataIn 1940, he arrived on April 21 and his birthday was also celebrated there, that year. This was his last visit as he fell ill and had to return to Kolkata. Tagore had written several memorable works during his stay at the hill retreat, including Chelebela, Nobojatok, Sesh Kotha, Bangla Bhashar Porichoy, Mongpu, Giribas, Sanai, Akash Prodip and Jonmodin. In Mongpu, Tagore used to stay in the house of Manmohan Sen (Husband of Maitreyi Devi), who was the chief chemist of the cinchona plantation. In 1944, this house was converted into a ‘Rabindra Smrity Bhavan.’ Later in 2009, the building was renovated and converted into a ‘Rabindra Museum.’ Also Read – Lightning kills 8, injures 16 in stateThe museum displays artifacts used by Tagore including pastels as well as homeopathy medicines. Manuscripts and paintings are also on display. Officials of the district administration garlanded the statue of the bard located on the premises of the museum. People from all walks of life also paid respects to Tagore on his birth anniversary. Owing to the ongoing elections and the Model Code of Conduct being in effect, the celebrations were toned down this time, stated officials of the district administration. Local artistes of the Bhutia Development Board and Gurung Development Board presented local dances like Singhi dance (lion dance by the Bhutia community).last_img read more

first_imgThe temptation was too great for him to handle. That was the explanation reportedly given by Greg Priore, the archivist in charge of protecting a special collection of rare books at the Carnegie Library in Pittsburgh. Priore reportedly walked out of the public library building with the rare books and took them to a partner to sell, a local bookstore owner, police said.Both Priore and John Schulman, the owner of the Caliban Book Shop, face multiple criminal charges. Books were stolen and also damaged to remove photos and maps.The stolen books, kept in the Oliver Room, a room that one needed special permission to access, included a 1787 first-edition book signed by Thomas Jefferson; a rare copy of The Journal of Major George Washington; and a version of Isaac Newton’s Principia, among the most influential books in science, said to be worth $900,000, according to a story in the New York Times.Front entrance of the Carnegie Library of Pittsburgh. Photo by Shizzy9989 CC BY-SA 3.0Prosecutors say that “Priore would sometimes use an X-Acto knife to cut maps and bookplates out of some books,” reported Pittsburgh’s NPR News. “They allege Priore walked out of the library with the items and took them to the bookstore a block away. They say the bookseller paid Priore up front and then pocketed the cash from items he could unload.”The pair’s crimes were uncovered after police working with the Allegheny County District Attorney’s Office began investigating the Oliver Room in June 2017. It was triggered by a scheduled appraisal that found “multiple items as being missing or damaged,” according to the criminal complaint filed in July 2018 against Priore and Schulman.The two men are accused of trafficking several hundred rare books.When the inventory was compared with the room’s contents from an appraisal done in 1991, authorities discovered that about 320 items were missing and 16 were vandalized by the removal of certain portions of the book.“Priore stated that he did not always conceal removing items from the premise,” detectives stated in the complaint. “If it were a small map or plate, he would place it in a manila folder. If it were a large map or plate, he would simply roll it up and carry it out. And with books, he would just carry them out.”The Caliban Book Shop is just a block away from the library.Interior of the main branch of Carnegie Library of Pittsburgh, a public library in Pittsburgh. The main library opened in 1895. Photo by Dllu CC BY-SA 4.0According to the detectives’ statement, Priore used the money he received from Schulman to “stay afloat.” He said he used it for rent and to pay his children’s tuition. Priore also told detectives he’d expected “fallout down the line.”Mysterious Books That Can’t Be ExplainedWhile admitting it was his idea in the first place, “I should have never done this,” he told investigators, according to the complaint. “I loved that room, my whole working life, and greed overcame me. I did it, but Schulman spurred me on.”Books on display.The two men are accused of trafficking several hundred rare books, maps, and other items worth more than $8 million, reports say. “More than $1 million worth of items, including the Newton volume, have been recovered,” the New York Times reported.The Carnegie Library of Pittsburgh is part of the city’s public library system. Priore oversaw about 30,000 items in the collection and controlled who had access to it, the affidavit said. According to one newspaper story, a library colleague of Priore’s was surprised to see Schulman looking at the collection and heard him discussing the value with Priore.Interior view, Carnegie Library of Pittsburgh.A separate legal action is taking place because Schulman is opposing the district attorney’s motion to freeze his bank accounts, court records show.A motion filed and signed by a judge froze two bank accounts related to John Schulman’s Caliban Book Shop. The prosecutors are arguing that the funds might eventually be needed to pay restitution.Read another story from us: Two Antique Portuguese Libraries Use Live Bats as Insect RepellantSchulman’s attorney said that the defense will need access to those accounts, and Schulman “will need to pay employees and bills, including rent, his mortgage and other costs,” reported Triblive. Nancy Bilyeau, a former staff editor at Entertainment Weekly, Rolling Stone, and InStyle, has written a trilogy of historical thrillers for Touchstone Books. For more information, go to www.nancybilyeau.com.last_img read more

first_imgWhat happens when a king goes missing? An epic new TV series will dramatize the power struggle which flared in Europe after Richard the Lionheart mysteriously disappeared in the 12th century. The series is titled Three Lions and has been created by Nicolas Deprost, CEO of Franco-Belgian production company Wild Horses. Nigel Williams (HBO’s Catherine The Great) has been hired to write the 10 parter.As quoted by Deadline, publicity states, “Richard the Lionheart’s absence and suspected death has created a power vacuum, Arthur his designated heir by law, is being denied his rightful place as King of England by his own grandmother, Eleanor of Aquitaine (Richard’s mother).”Tomb of Richard the LionheartInter-family conflict is something that characterizes Richard’s bloodline. His father was Henry II, who Richard previously fought against — alongside France’s Philip II — in a battle for dominance.Eleanor “has no intention of relinquishing any of her power and influence. If Richard is dead, Eleanor is determined that her next son, John Lackland, will be crowned King and her status as the Regent Queen will remain unchallenged.” This not only sets her against King Philip but also Constance, Arthur’s mother, who rules the roost over in Brittany.The blurb ends by summarizing what viewers have in store. “Eleanor and Constance are two powerful, independent and driven women who will stop at nothing to place their own son on the throne. Only one can become the King of England.”Richard the Lionheart statueDespite Richard being a presence in the story, it appears the focus of the drama will be the simmering tensions back home. Deprost comments that, “Loyalties, rivalries, lust, conspiracies and the thirst for power are often the focus of history, but Three Lions also shines a light on powerful women in the medieval period and the strength of a mother’s love.”He highlights this by adding, “Constance is not well known in British history, but this passionate, liberal, strong-hearted Duchess played a crucial role in shaping England and France as we know it today.”But will King Richard himself appear in proceedings? The Lionheart, or “Coeur de Lion” was a central figure of the Third Crusade (1189 – 92), taking on Saladin, the first Sultan of Egypt and Syria. Richard spent more time abroad than he did ruling over England, living in the country of his reign for a mere matter of months.Richard the Lionheart statue. It stands on a granite pedestal in Old Palace Yard outside the Palace of Westminster, London.Born in Oxford to French parents in 1157, it seems didn’t have much time for the place. The website Historic UK writes, “it is doubtful that he could actually speak the English language. He once remarked that he would have sold the whole country if he could have found a buyer.”If he does appear onscreen, Richard should cut an impressive figure. “Richard was tall, perhaps 6ft 5in, with red-to-auburn hair and piercing blue eyes,” wrote History Today. “He had a sense of humour and, according to a disapproving clerical chronicler, could keep his companions in fits of laughter. He could be kind, charming and generous, and alternatively ruthlessly cruel, and like all his family he had a fearsome temper.”What of his whereabouts during the course of Three Lions? It turns out the King was shipwrecked off the capital city of Trieste, in the Friuli Venezia Giulia region of northeast Italy. It sounds scenic, but he didn’t have a great time.Richard the Lionheart marches towards Jerusalem, by James William Glass (1850)He was first imprisoned by the Duke of Austria and then ransomed by Germany’s Henry VI at a major cost to the public purse. A “quarter of every man’s income for a whole year” was needed to meet the cost of an eye-watering 150,000 marks.After returning to England in 1194, he saw out the remainder of his days in typical fashion. Having been “crowned for a second time, fearing that the ransom payment had compromised his independence” according to BBC History, he “went to Normandy… His last five years were spent in intermittent warfare against Philip II. While besieging the castle of Châlus in central France he was fatally wounded and died on 6 April 1199.”King Richard the Lionheart marrying Robin Hood and Maid Marian on a plaque outside Nottingham Castle. Photo by RichardUK2014 CC BY-SA 3.0All this would be enough for a TV show in itself — indeed, ITV in the UK produced a Richard the Lionheart series in 1962-63 starring Dermot Walsh. For this tale however producers are aiming for Game of Thrones-style intrigue. No casting has been announced as yet.Read another story from us: Keanu Reeves and Alex Winter Officially Announce Bill & Ted 3“The Middle Ages is painfully close to us, and, at the same time, a completely foreign country of which we know nothing,” Williams remarked. “For a writer, this period is both a gift and a challenge – and one I am happy to embrace.”Three Lions is reportedly going into production next year.last_img read more

first_img“Bohemian Rhapsody” by Queen was originally released in 1975 and it quickly became one of the world’s most famous rock anthems. Today, in the U.K. alone, “Bohemian Rhapsody” is the third-highest selling single of all times, following Elton John’s “Candle in the Wind” and runner up Band Aid’s “Do They Know It’s Christmas?” The success for Queen happened despite their record label’s initial assumption that “Bohemian Rhapsody” would be a failure.The bandmates were told their single was too long, too complicated, and something that radio stations would never add to playlists. Yet they did. It was also the first track that combined operatic elements in its composition.Freddie Mercury singing, 1977. Photo by Carl Lender CC BY-SA 3.0Enter “Hey Jude” by the Beatles; though very different in sound, it shares a few intriguing similarities with Queen’s masterpiece. Originally released in 1968, with a “na na na” outro lasting four minutes within the single’s seven minutes and 11 seconds (“Bohemian Rhapsody” is five minutes and 55 seconds) it was at the time the longest single to have ever been released.AdChoices广告inRead invented by TeadsHowever, radio stations settled for it without many discussions. In the U.S. alone, “Hey Jude” became the fourth-best selling hit of the Beatles, though it just may be their best earning one considering the prices of other of their records.Queen on stage at the Oakland Arena, Oakland, California, July 1980. Photo by Mark James Miller CC BY-SA 3.0Both “Bohemian Rhapsody” and “Hey Jude” were songs about relationships, though, in the case of the latter, it’s all the more clear. Paul McCartney dedicated “Hey Jude” to Julian, then the five-year-old son of Cynthia and John Lennon, as the pair was splitting up following John Lennon’s affair with Yoko Ono.Queen’s “Bohemian Rhapsody” was also “about relationships” although beyond that, when asked on the song’s meaning, Freddie himself had always remained quite reserved with providing more substantial answers.What’s certainly known is that the melody had him haunted, perhaps just like his sexuality, since the late 1960s. It was there in his mind and he would occasionally play bits from the Rhapsody on the piano, a moment depicted in the recent Queen biopic.Paul McCartney. Photo by Oli Gill CC BY-SA 2.0More than that, when it finally came for “Bohemian Rhapsody” to see the light of the day — be recorded in a studio — Mercury reportedly used the same piano which McCartney used for “Hey Jude” seven years prior to that. In fact, the piano in question has famously served an array of top-notch performers of the era, including David Bowie, Supertramp, Nilsson, and the Rolling Stones.Described as a century-old Bechstein Grand Piano, a bit difficult to play but which produced a really genuine and clear sound, the instrument lured famous performers of the day to come to the Trident Studios in London’s Soho district, where it stayed since the mid-1960s.Bechstein Art Nouveau grand piano, 1902. Photo by Count de money CC BY-SA 3.0According to LiveAuctioneers, the Piano was purchased by the studios only in 1986, as “they had previously rented it from Samuels from the mid-1960s.”It was not just “Hey Jude” and “Bohemian Rhapsody” that were recorded with its help, but wholesome albums that changed the fabric of the music industry such as the Beatles’ “White Album”, David Bowie’s “Space Oddity” and George Harrison’s solo album “All Things Must Pass” so to name just three. Other top-selling singles that used the legendary Bechstein include Mary Hopkins’ “Those Were the Days” and Lou Reed’s smash hit “Perfect Day”.Bechstein advertisement poster“The sheer quantity, quality, and diversity of the hit songs that the piano has been used on, must qualify it as being the most historical instrument of modern times,” and its value today has been estimated at at least $400,000, writes LiveAuctioneers.Read another story from us: Mary Austin – The Woman Freddie Mercury Loved and Left Most of his Fortune ToFinally, while for the Beatles all that needed was four takes to have the final version of “Hey Jude,” the four bandmates of Queen practiced and played a lot before recording the Rhapsody in a studio.They would spend a month locked in a house in the English courtyard so as to perfect playing their greatest hit and those fierce, extravagant vocals. It was the summer of 1975, and things were just about to really change for the band.last_img read more

first_img 3 min read May 15, 2009 Opinions expressed by Entrepreneur contributors are their own. By Zack SternOne of your biggest per-employee infrastructure costs comes from money tied up in software licenses. If you add new people, you could cough up thousands of dollars right then. And that money you paid stops working for you as soon as you lose employees, as those licenses sit unused.Depending on your software, you can address both issues by buying subscriptions, in bulk, choosing used licenses, or selling full licenses when no longer needed. Keep these options in mind, especially if you’re scaling temporary workers.Pay Monthly For SoftwareMany companies offer monthly subscriptions for software licenses. On the server side, for example, this model can save a big, single fee for per-user Exchange licenses. But a monthly plan for workstations can also help you save.Microsoft offers these options for much of its software, including Office and Windows itself. If your business has five or more workstations, you can use the Open Value option to save. You’ll choose between a subscription fee or a bulk-rate, up-front perpetual license, letting you choose to save in the short term or long term.Microsoft, like other companies I contacted for this article, didn’t quote specific cost numbers since they vary with company needs. You’ll have to get a quote for your business to get a direct sense of savings.You’ll also agree to a three-year commitment for Microsoft’s subscription plan. However, you can scale the number of licenses during that time.Contact your other software companies to see what kinds of licensing options they offer. Adobe, for example, doesn’t yet sell a subscription license. However, the company recently tested subscriptions in Australia and is currently evaluating its results.But like Microsoft and most other companies, Adobe still offers volume licensing discounts. Depending on your needs and volume, you could save between about 5 to 20 percent over buying individual copies of software. Contact Adobe for a specific quote for your business.Buy and Sell Unused LicensesIf you bought full licenses up-front but no longer need some, sell them. Your specific rights can vary. Adobe, for example, has no problem with you selling unused licenses, just as long as you don’t sell volume-discount licenses to individual customers. (You’d have to sell those to a volume customer.)Microsoft doesn’t allow customers to sell licenses. Consult your software vendors–or a legal professional–to determine your rights.Regardless of Microsoft’s dislike, some companies, including Discount Licensing, offer ways to facilitate these sales. Depending on the product and customer, they’ll either act as a matchmaker, brokering a deal between two parties, or buy your licenses outright.And these companies offer a cheaper alternative to buying new licenses. If brokering, a deal could take a few months to come together. However, if the company is holding a license you need, you could buy it that day. Discount Licensing says you’ll save about 10 to 15 percent off normal license costs.Zack Stern is a freelance writer and editor based in San Francisco. Register Now » Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global Growing a business sometimes requires thinking outside the box.last_img read more

first_imgMay 30, 2017 Enroll Now for Free 3 min read British Airways had a rough weekend.Due to a power surge early Saturday morning and a backup that failed to work, the airline’s computer systems broke down. The crash prompted British Airways to cancel all departing flights from Heathrow and Gatwick airports, effectively stranding 75,000 people. And once the passengers arrived at their destinations, there was no guarantee that their luggage would be waiting for them.It was a chaotic and ultimately expensive mishap for British Airways. The market value of IAG, the airline’s parent company, dropped by about $643,550,000. Not only that, but The Guardian reports that customers inconvenienced by the IT issues had to pay up to $2,059 in additional travel costs, leaving the company with a hefty compensation $192 million compensation bill.Related: These 10 Countries Will See the Most Business Travelers in the Next DecadeIf you’re sleeping on the floor of an airport terminal, of course you aren’t going to have a ton of understanding for the organization that put you in that position. But it wasn’t just disgruntled passengers — the response from rival airline, Ireland’s Ryanair was particularly merciless.Breaking news: BA appoints new head of IT…. #ShouldHaveFlownRyanair pic.twitter.com/pR5lwJmr95— Ryanair (@Ryanair) May 28, 2017A peek into the company’s Tweets & Replies tab on Twitter shows a raft of customer service messages with a heavy use of the words “sorry” and “apologise.” CEO Alex Cruz also made a video apology.Related: 5 Ways to De-Stress Your Business Travel“We absolutely, profusely apologize for these events,” Cruz said. “We are absolutely committed to making sure that we fulfill our obligations, particularly from a passenger compensation point of view. … We are now focusing on making sure that everyone’s needs are addressed. We will make an in-depth investigation to make sure we get to the bottom of exactly why this happened and we will react. This will not happen again at British Airways.”Our Chairman and CEO, Alex Cruz, apologises for the disruption caused by the recent IT system issues and… https://t.co/DRqwuM3SvF— British Airways (@British_Airways) May 29, 2017Cruz is saying all the right things, and it would seem that his team is working tirelessly to make sure that each customer is taken care of. But what the experience of British Airways teaches us is that we need to think carefully about where resources can best be utilized. Think about the systems and structures that you can’t do without and always make sure that they are up to date. If you can have the most current technology, an investment now could save you a major headache later.Better that the glitch never happened at all — but if your company is faced with a snafu of this magnitude, the best move is to be honest, admit what went wrong and keep your customers informed.center_img Free Workshop | August 28: Get Better Engagement and Build Trust With Customers Now This hands-on workshop will give you the tools to authentically connect with an increasingly skeptical online audience.last_img read more

first_img by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeKelley Blue Book5 Mid-engine Corvettes That Weren’tKelley Blue BookUndoVerizon WirelessThis new phone will blow your mind.Verizon WirelessUndoTODAYPolice Identify Girl Licking Ice Cream Tub In Viral VideoTODAYUndoMy Food and FamilyHealthy, Homemade Drunken Thai Noodles In Just 20 MinutesMy Food and FamilyUndo247 SportsRanking The Highest-Paid NBA Players In 2019247 SportsUndoCIO for DOMOBrandPost: How AI Can Make You a Next-Generation CIOCIO for DOMOUndoAdvertisement Amazon Prime Day is in full swing and the retailer is offering some generous deals on gaming machines.Today only, Amazon has the Asus TUF FX505 Gaming Laptop on sale for $579.99. Traditionally priced at $700, that’s $120 off. It’s the lowest price we’ve ever seen for this gaming machine. Buy the Asus TUF FX505 Gaming Laptop for $579.99 at AmazonIt features a 15.6-inch IPS 1080p display and houses a 2.1 GHz Ryzen 5 3550H quad-core CPU coupled with 8GB of RAM. Rounding out its hardware specs is a Radeon Rx 560X GPU with 8GB of dedicated memory and 256GB of on-board SSD storage.MacBook Air vs MacBook Pro: Which 13-inch MacBook Is Right For You?Apple’s entry-level MacBook Air and Pro look pretty similar, but our testing proved they differ in crucial ways.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Which Cheap Tablet Is Best? Amazon Fire 7 vs Walmart Onn02:45关闭选项Automated Captions – en-USAutomated Captions – en-USAutomated Captions – en-US facebook twitter 发邮件 reddit 链接https://www.laptopmag.com/articles/prime-day-slashes-120-asus-tuf-gaming-laptop?jwsource=cl已复制直播00:0003:4603:46 We reviewed a similar model, the TUF FX504 and were impressed by its good gaming performance and cooling system. Although we thought its battery life could be better, we gave it a 3 out of 5 rating for its overall solid performance and audio. Made of durable plastic with a faux-aluminum brushing, and a reflective Asus logo on its lid, the TUF FX505 is nearly identical to the TUF FX504. The only difference is that it doesn’t have the red, angular lined patterned paint on the lid.At 4.9 pounds and measuring 14.2 x 10.3 x 1.1 inches, it’s thinner yet thicker than other gaming laptops in its class. By comparison, the Acer Nitro 5 Spin is ths same 4.9 pounds and 15 x 10.2 x 0.7 inches. In terms of performance, the FX504’s Core i5-8300H CPU scored 12,038, which surpassed the HP Pavilion Power 15t (11,214) but trailed the entry-level gaming average (12,718) and the Acer Nitro 5 Spin (13,477).The TUF FX505’s Ryzen 5 four-core CPU and 8GB of RAM combo should offer ample power for demanding workloads and today’s games. So if you need a capable gaming machine for a stellar price, act fast to score this Asus TUF machine at an excellent price.  Asus TUF Gaming LaptopBest Amazon Prime Day Laptop Deals last_img read more

first_imgMulti-Process Firefox: everything you need to know by Martin Brinkmann on July 22, 2016 in Firefox – Last Update: May 17, 2019 – 56 commentsAfter years of development and several delays, multi-process Firefox, also known as Electrolysis or e10S, is about to be enabled for a subset of Firefox stable users.The following guide provides you with information about Firefox’s multi-process architecture. It explains what the feature offers, preferences and switches for it, covers add-on compatibility, and takes a look at the future of the feature.Mozilla plans to enable the multi-process architecture for a subset of Firefox Stable users when the browser reaches version 48. If things go as planned, Firefox 48 will be released on August 2, 2016.The multi-process rollout has started, and is ongoing (as of Firefox 52). Mozilla plans to increase the number of content processes to four for the stable population in Firefox 54.Multi-Process FirefoxElectrolysis functionality hosts, renders, or executes web related content in background child processes which communicate with the “parent” Firefox browser via various ipdl protocols.The Multi-process architecture improves the browser’s stability, performance and security by separating tasks into processes.The first iteration of multi-process Firefox moves NPAPI plugins, media playback and web content to child processes thus separating them from the browser’s core.Find out if Multi-process support is enabledThe easiest way to find out whether multi-process Firefox is enabled is the following one:Load about:support in the Firefox address bar.Locate “Multiprocess Windows” under Application Basics near the top.It should read enabled or disabled, and gives you a direct answer about the state of multi-process functionality in the browser.Enabling Electrolysis in FirefoxIf multi-process support is not enabled yet in Firefox, you may enable it manually. This is true even if you run Firefox 47 Stable as the functionality is already there.Before you do so, you may want to run compatibility checks for add-ons though. If you don’t run add-ons, about 40% of Firefox users don’t according to Mozilla, you may skip the step.Verifying add-on compatibilityWhile you can jump into water right away by enabling Electrolysis without verifying compatibility first, it is highly suggested to verify that all important add-ons are compatible with e10s before you do so.You may check out the Are We e10S Yet site which lists top add-ons and their compatibility with e10s. The majority of Firefox add-ons are not tested though so that you may be none the wiser after checking your add-ons on the site.What you can do, is create a secondary profile in Firefox, copy all extensions of the first profile to it, and enable e10s for that secondary profile.This is far from ideal though. An alternative is to disable all add-ons, enable e10s, and enable extensions one by one to find out whether they are compatible.Enable / Disable Electrolysis in FirefoxTo enable or disable multi-process Firefox, do the followingType about:config in the browser’s address bar.Confirm that you will be careful.Search for browser.tabs.remote.autostart.Double-click on the preference.Setting the value of browser.tabs.remote.autostart to true enables the multi-process architecture in Firefox, setting it to false disables it.Note: From Firefox 68 onward, setting the preference to False has no effect. Firefox sets the preference to True automatically regardless of user preference.Please note that you need to restart the browser when you change the preference’s value.Some configurations, if accessibility is used or add-ons are incompatibility, prevent Electrolysis from being enabled.The about:support page mentioned previously list the reason so that you know why multi-process is not working.You may force-enable multi-process functionality in Firefox. I recommend that you backup your user profile before you do.Type about:config in the browser’s address bar and hit enter.Right-click and select New > Boolean.Name it browser.tabs.remote.force-enable.Set its value to true.Starting in Firefox 68, the preference is no longer available.Note that forcing compatibility may have a big impact on performance if add-ons are incompatible with e10s.There is another preference that you may need to change on about:config.Search for extensions.e10sMultiBlockedByAddonsSet the preference to false.This prevents the blocking of multiple content processes by add-ons.Changing the number of content processesMozilla Firefox uses one content process by default right now when multi-process Firefox is enabled. Mozilla plans to change that in Firefox 54 by increasing the number of content processes to 4 in that version.You can modify the count right now, to raise or decrease the limit. Note that Firefox will ship with an option in the browser’s settings eventually that lets you do that.Type about:config in the browser’s address bar and hit enter.Search for dom.ipc.processCount.Double-click on the value, and change it. The number you enter is the number of content processes that Firefox will use.When Multiprocess Windows is enabledYou can check the about:support page in Firefox to find out whether multi-process is enabled or not.You will notice several firefox.exe processes when you run a process manager, e.g. the Windows Task Manager which highlights that Electrolysis is enabled.Firefox should for the most part run just like before. Ideally, enabling multi-process functionality should improve the browser’s performance and stability right away.You may however notice a higher than usual RAM usage. Mozilla confirmed that Firefox with Electrolysis will use about 20% more RAM.You may change how many processes Firefox uses for its multi-process functionality.The futureMozilla will continue to work on multi-process Firefox after the initial roll out of the feature. The organization plans to bring sandboxing to Firefox which, on Windows, is based on the Chromium sandbox that Google uses in Chrome. This sandbox will improve security significantly when enabled.Now You: What’s your take on the coming roll out of e10s in Firefox?SummaryArticle NameMulti-Process Firefox: everything you need to knowDescriptionAfter years of development and several delays, multi-process Firefox, also known as Electrolysis or e10S, is about to be enabled for a subset of Firefox stable users.Author Martin BrinkmannPublisher Ghacks Technology NewsLogo Advertisementlast_img read more